منابع مشابه
Treating to target: ready, fire, aim.
Evidence • Multiple cohort studies found PC patients did not achieve SMTs (ie, cholesterol, blood pressure [BP], glycated hemoglobin [HbA1c]). -Of 1706 patients with diabetes mellitus (DM), 7.3% achieved 3 targets (HbA1c < 7%, BP < 130/80 mm Hg, and cholesterol < 5.18 mmol/L)1; of 1701 Canadians, 24% had low-density lipoprotein (LDL) levels of < 2 mmol/L2; and of 3167 patients with coronary art...
متن کاملFire, Aim… Ready? Alberta's Big Bang Approach to Healthcare Disintegration.
Alberta's abolition in 2008 of its health regions and the creation of Alberta Health Services (AHS) was a bold move, but the reasons for the change remain hazy. The stated goals were to "help make Alberta's … system more effective and efficient" and to "provide equitable access to health services and long-term sustainability." Data show, however, that Alberta's health regions were already perfo...
متن کاملReady! Aim! Fire! targeting the right medical science journal
OBJECTIVE Inadvertently submitting a paper to a journal that is unlikely to publish it is a waste of resources and ultimately delays dissemination of one's research. A high proportion of manuscripts are rejected by their author's first-choice journal. The aim of the present work was to review guidance provided within the literature for journal selection that might minimize the chance of manuscr...
متن کاملTargeting cancer with bugs and liposomes: ready, aim, fire.
One of the major challenges facing cancer therapy today is achieving specificity. Current efforts to meet this challenge are focused on developing targeted therapeutics specific to the cancer cell. An alternative approach is to selectively deliver cytotoxic agents to the tumor site. With this end in mind, liposomes optimized for physical robustness have been developed and used clinically as dru...
متن کاملGLUT4 ready to go
GLUT4 ready to go esicles containing the glucose transporter GLUT4 travel rapidly on a microtubule network that lies just under the plasma membrane in resting cells, according to results from Lizunov et al. (page 481). The vesicles occasionally touch the plasma membrane and, when stimulated by insulin, quickly fuse with it. GLUT4 is sequestered in vesicles in resting cells. Insulin exposure ind...
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ژورنال
عنوان ژورنال: Plant Signaling & Behavior
سال: 2008
ISSN: 1559-2324
DOI: 10.4161/psb.3.7.6098